KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GYS1
All Species:
14.85
Human Site:
S710
Identified Species:
23.33
UniProt:
P13807
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P13807
NP_002094.2
737
83786
S710
T
S
G
S
K
R
N
S
V
D
T
A
T
S
S
Chimpanzee
Pan troglodytes
XP_520790
703
80912
R676
D
E
E
E
E
A
E
R
D
R
L
N
I
K
S
Rhesus Macaque
Macaca mulatta
Q8MJ26
737
83768
S710
T
S
G
S
K
R
N
S
V
D
T
A
T
S
S
Dog
Lupus familis
XP_534869
703
80957
R676
N
E
E
E
E
A
E
R
D
R
L
N
I
K
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1E4
738
83908
S711
G
G
S
K
R
S
N
S
V
D
T
G
P
S
S
Rat
Rattus norvegicus
A2RRU1
738
84053
S711
G
G
S
K
R
S
N
S
V
D
T
G
P
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505471
733
83148
S706
Q
S
G
A
K
R
G
S
V
D
T
A
P
S
S
Chicken
Gallus gallus
XP_416432
704
81032
E674
E
R
Y
D
E
D
E
E
A
E
R
D
R
Q
N
Frog
Xenopus laevis
NP_001084863
702
80811
R675
D
E
D
E
E
A
E
R
D
R
Q
N
I
K
S
Zebra Danio
Brachydanio rerio
NP_957474
700
80455
K674
D
E
D
L
E
A
E
K
D
R
V
N
I
R
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VFC8
709
81735
S675
R
P
H
S
E
P
P
S
P
T
S
S
R
H
T
Honey Bee
Apis mellifera
XP_624707
692
79590
A666
S
R
H
T
T
P
A
A
S
V
H
G
S
D
E
Nematode Worm
Caenorhab. elegans
Q9U2D9
672
76441
R646
P
D
V
D
K
I
M
R
D
N
E
G
K
V
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P23337
708
80492
D682
Q
D
A
N
N
A
D
D
Y
F
N
L
S
T
N
Red Bread Mold
Neurospora crassa
O93869
706
80888
F680
E
D
P
E
E
Y
P
F
P
L
T
L
K
Q
R
Conservation
Percent
Protein Identity:
100
68.6
99
69.3
N.A.
96.6
96.6
N.A.
90
71
69.3
78.1
N.A.
55
56.4
49.6
N.A.
Protein Similarity:
100
81.8
99.5
82.5
N.A.
98.5
98.5
N.A.
95.2
84.1
82.5
86.5
N.A.
71
70.1
65.8
N.A.
P-Site Identity:
100
6.6
100
6.6
N.A.
46.6
46.6
N.A.
73.3
0
6.6
0
N.A.
13.3
0
6.6
N.A.
P-Site Similarity:
100
13.3
100
13.3
N.A.
53.3
53.3
N.A.
80
20
13.3
6.6
N.A.
40
26.6
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
50
51.1
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
67.1
67
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
7
0
34
7
7
7
0
0
20
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
20
20
14
14
0
7
7
7
34
34
0
7
0
7
0
% D
% Glu:
14
27
14
27
47
0
34
7
0
7
7
0
0
0
7
% E
% Phe:
0
0
0
0
0
0
0
7
0
7
0
0
0
0
0
% F
% Gly:
14
14
20
0
0
0
7
0
0
0
0
27
0
0
0
% G
% His:
0
0
14
0
0
0
0
0
0
0
7
0
0
7
0
% H
% Ile:
0
0
0
0
0
7
0
0
0
0
0
0
27
0
0
% I
% Lys:
0
0
0
14
27
0
0
7
0
0
0
0
14
20
0
% K
% Leu:
0
0
0
7
0
0
0
0
0
7
14
14
0
0
0
% L
% Met:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% M
% Asn:
7
0
0
7
7
0
27
0
0
7
7
27
0
0
14
% N
% Pro:
7
7
7
0
0
14
14
0
14
0
0
0
20
0
7
% P
% Gln:
14
0
0
0
0
0
0
0
0
0
7
0
0
14
7
% Q
% Arg:
7
14
0
0
14
20
0
27
0
27
7
0
14
7
7
% R
% Ser:
7
20
14
20
0
14
0
40
7
0
7
7
14
34
54
% S
% Thr:
14
0
0
7
7
0
0
0
0
7
40
0
14
7
7
% T
% Val:
0
0
7
0
0
0
0
0
34
7
7
0
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
0
0
7
0
0
7
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _